Pesticidal composition comprising fenamidone and an insecticide compound

ABSTRACT

A composition comprising fenamidone (a) and an insecticide compound (b) in a (a)/(b) weight ratio of from 1/1000 to 1000/1. 
     A composition further comprising an additional fungicidal compound. 
     A method for preventively or curatively combating the pests and diseases of crops by using this composition

The present invention relates to novel pesticidal compositionscomprising a pyridylethylbenzamide derivative and an insecticidecompound. The present invention also relates to a method of combating orcontrolling pests by applying at a locus infested or liable to beinfested such a composition.

European patent application EP-629616 discloses numerous2-imidazolin-5-one derivatives including fenamidone, and their use asfungicide. The possibility of combining one or more of these2-imidazolin-5-one derivatives with known fungicidal products to developa fungicidal activity is disclosed. No mention is made of a possibleassociation of fenamidone with an insecticide active ingredient.

International patent application WO-99/027788 discloses compositionscomprising 2-imidazolin-5-one derivatives according to the presentinvention in mixture with other fungicide active ingredients and theiruse as fungicide. No mention is made of mixtures comprising fenamidonewith an insecticide active ingredient.

In international patent application WO-2007/101547 there are genericallydisclosed numerous mixtures of some phthalamide insecticide compoundswith known fungicide substances. The association of these insecticidecompounds with fenamidone has not been specifically disclosed nor hasbeen subject to any experimentation. Such an association does not formpart of the present invention.

It is always of high-interest in agriculture to use novel pesticidalmixtures showing a broader scope of activity and a fungicide orinsecticide synergistic effect in order notably to avoid or to controlthe development of resistant strains to the active ingredients or to themixtures of known active ingredients used by the farmer while minimisingthe doses of chemical products spread in the environment and reducingthe cost of the treatment.

We have now found some novel pesticidal compositions which possess theabove mentioned characteristics.

Accordingly, the present invention relates to a composition comprising

a) fenamidone; andb) an insecticide compound;in a (a)/(b) weight ratio of from 1/1000 to 1000/1;provided that insecticide B compound is different from compounds ofgeneral formula (II)

wherein

-   -   Hal represents a chlorine atom, a bromine atom or a iodine atom;    -   R represents hydrogen or methyl and * may represent a carbon        atom in R- or S-configuration.

The composition according to the present invention provides asynergistic effect. This synergistic effect allows a reduction of thechemical substances spread into the environment and a reduction of thecost of the pesticidal treatment.

In the context of the present invention, the term “synergistic effect”is defined by Colby according to the article entitled “Calculation ofthe synergistic and antagonistic responses of herbicide combinations”Weeds, (1967), 15, pages 20-22.

-   -   The latter article mentions the formula

$E = {x + y - \frac{x*y}{100}}$

in which E represents the expected percentage of inhibition of the pestfor the combination of the two pesticides at defined doses (for exampleequal to x and y respectively), x is the percentage of inhibitionobserved for the pest by the compound (a) at a defined dose (equal tox), y is the percentage of inhibition observed for the pest by thecompound (b) at a defined dose (equal to y). When the percentage ofinhibition observed for the combination is greater than E, there is asynergistic effect.

The latter article also mentions the formula:

$E = {x + y + z - \frac{x*y*z}{100}}$

in which E represents the expected percentage of inhibition of the pestfor the combination of the three pesticides at defined doses (forexample equal to x, y and z respectively), x is the percentage ofinhibition observed for the pest by the compound (a) at a defined dose(equal to x), y is the percentage of inhibition observed for the pest bythe compound (b) at a defined dose (equal to y) and z is the percentageof inhibition observed for the pest by the compound (c) at a defineddose (equal to z). When the percentage of inhibition observed for thecombination is greater than E, there is a synergistic effect.

The composition according to the present invention comprises aninsecticide compound (b). Suitable insecticide includes:

The composition according to the present invention comprises aninsecticide compound (b). Suitable insecticide are chosen in thefollowing groups:

b1) acetylcholine receptor agonists/antagonists such aschloronicotinyls/neonicotinoids, nicotine, bensultap or cartap. Suitableexamples of chloronicotinyls/neonicotinoids include acetamiprid,clothianidin, dinotefuran, imidacloprid, nitenpyram, nithiazine,thiacloprid, thiamethoxam, imidaclothiz and(2E)-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3,5-dimethyl-N-nitro-1,3,5-triazinan-2-imine;b2) acetylcholinesterase (AChE) inhibitors such as carbamates andorganophosphates. Suitable examples of carbamates include alanycarb,aldicarb, aldoxycarb, allyxycarb, aminocarb, bendiocarb, benfuracarb,bufencarb, butacarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran,carbosulfan, chloethocarb, dimetilan, ethiofencarb, fenobucarb,fenothiocarb, formetanate, furathiocarb, isoprocarb, metam-sodium,methiocarb, methomyl, metolcarb, oxamyl, phosphocarb, pirimicarb,promecarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb,XMC and xylylcarb. Suitable examples of organophosphates includeacephate, azamethiphos, azinphos (-methyl, -ethyl), bromophos-ethyl,bromfenvinfos (-methyl), butathiofos, cadusafos, carbophenothion,chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos(-methyl/-ethyl), coumaphos, cyanofenphos, cyanophos, demeton-5-methyl,demeton-5-methylsulphon, dialifos, diazinon, dichlofenthion,dichlorvos/DDVP, dicrotophos, di-methoate, dimethylvinphos,dioxabenzofos, disulfoton, EPN, ethion, ethoprophos, etrimfos, famphur,fenamiphos, fenitrothion, fensulfothion, fenthion, flupyrazofos,fonofos, formothion, fosmethilan, fosthiazate, heptenophos, iodofenphos,iprobenfos, isazofos, isofenphos, isopropyl O-salicylate, isoxathion,malathion, mecarbam, methacrifos, methamidophos, methidathion,mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion(-methyl/-ethyl), phenthoate, phorate, phosalone, phosmet, phosphamidon,phosphocarb, phoxim, pirimiphos (-methyl/-ethyl), profenofos, propaphos,propetamphos, prothiofos, prothoate, pyraclofos, pyridaphenthion,pyridathion, quinalphos, sebufos, sulfotep, sulprofos, tebupirimfos,temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, triclorfonand vamidothion;b3) sodium channel modulators/voltage-gated sodium channel blockers suchas pyrethroids and oxadiazines. Suitable examples of pyrethroids includeacrinathrin, allethrin (d-cis-trans, d-trans), beta-cyfluthrin,bifenthrin, bioallethrin, bioallethrin-5-cyclopentyl-isomer,bioethanomethrin, biopermethrin, bioresmethrin, chlovaporthrin,cis-cypermethrin, cis-resmethrin, cis-permethrin, clocythrin,cycloprothrin, cyfluthrin, cyhalothrin, cypermethrin (alpha-, beta-,theta-, zeta-), cyphenothrin, DDT, deltamethrin, empenthrin (IR-isomer),esfenvalerate, etofenprox, fenfluthrin, fenpropathrin, fenpyrithrin,fenvalerate, flubrocythrinate, flucythrinate, flufenprox, flumethrin,fluvalinate, fubfenprox, gamma-cyhalothrin, imiprothrin, kadethrin,lambda-cyhalothrin, metofluthrin, permethrin (cis-, trans-), phenothrin(1R-trans isomer), prallethrin, profluthrin, protrifenbute,pyresmethrin, resmethrin, RU 15525, silafluofen, tau-fluvalinate,tefluthrin, terallethrin, tetramethrin (1R-isomer), tralocythrin,tralomethrin, transfluthrin, ZXI 8901 and pyrethrins (pyrethrum).Suitable example of oxadiazines includes indoxacarb;b4) acetylcholine receptor modulators such as spinosyns. Suitableexample of spinosyns includes spinosad;b5) GABA-gated chloride channel antagonists such as cyclodieneorganochlorines and fiproles. Suitable examples of cyclodieneorganochlorines include camphechlor, chlordane, endosulfan, gamma-HCH,HCH, heptachlor, lindane and methoxychlor. Suitable examples of fiprolesinclude acetoprole, ethiprole, fipronil and vaniliprole;b6) chloride channel activators such as mectins. Suitable examples ofmectins include abamectin, avermectin, emamectin, emamectin-benzoate,ivennectin, lepimectin, milbemectin and milbemycin;b7) juvenile hormone mimetics such as diofenolan, epofenonane,fenoxycarb, hydroprene, kinoprene, methoprene, pyriproxifen, triprene;b8) ecdysone agonists/disruptors such as diacylhydrazines. Suitableexamples of diacylhydrazines include chromafenozide, halofenozide,methoxyfenozide and tebufenozide;b9) inhibitors of chitinbiosynthesis such as benzoylureas, buprofezinand cyromazine. Suitable examples of benzoylureas include bistrifluoron,chlofluazuron, diflubenzuron, fluazuron, flucycloxuron, flufenoxuron,hexaflumuron, lufenuron, novaluron, noviflumuron, penfluoron,teflubenzuron and triflumuron;b10) inhibitors of oxidative phosphorylation, ATP disruptors such asorganotins and diafenthiuron. Suitable examples of organotins includeazocyclotin, cyhexatin and fenbutatin oxide;b11) decouplers of oxidative phosphorylation by disruption of the Hproton gradient such as pyrroles and dinitrophenols. Suitable example ofpyrroles includes chlorfenapyr. Suitable examples of dinitrophenolsinclude binapacyrl, dinobuton, dinocap and DNOC;b12) site I electron transport inhibitors such as METIs, hydramethylnoneand dicofol. Suitable examples of METIs include fenazaquin,fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad;b13) site II electron transport inhibitors such as rotenone;b14) site III electron transport inhibitors such as acequinocyl andfluacrypyrim;b15) microbial disrupters of the intestinal membrane of insects such asBacillus thuringiensis strains;b16) inhibitors of lipid synthesis such as tetronic acids and tetramicacids. Suitable examples of tetronic acids include spirodiclofen,spiromesifen and spirotetramat. Suitable example of tetramic acidsincludescis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-ylethyl carbonate (alias: carbonic acid,3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-ylethyl ester (CAS Reg. No.: 382608-10-8)b17) carboxamides such as flonicamid;b18) octopaminergic agonists such as amitraz;b19) inhibitors of the magnesium-stimulated ATPase such as propargite;b20) ryanodin receptor agonists such as phthalamides or rynaxapyr.Suitable example of phthalamides includesN²-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N¹-[2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1,2-benzenedicarboxamide(i.e. flubendiamide, CAS reg. No.: 272451-65-7);b21) nereistoxin analogues such as thiocyclam hydrogen oxalateandthiosultap-sodium;b22) biologics, hormones or pheromones such as azadirachtin, Bacillusspec., Beauveria spec., codlemone, Metarrhizium spec., Paecilomycesspec., thuringiensis and Verticillium spec;b23) active compounds having unknown or non-specified mechanisms ofaction such as fumigants, selective feeding inhibitors, mite growthinhibitors, amidoflumet; benclothiaz, benzoximate, bifenazate,bromopropylate, buprofezin, chinomethioat, chlordimeform,chlorobenzilate, chloropicrin, clothiazoben, cycloprene, cyflumetofen,dicyclanil, fenoxacrim, fentrifanil, flubenzimine, flufenerim,flutenzin, gossyplure, hydramethylnone, japonilure, metoxadiazone,petroleum, piperonyl butoxide, potassium oleate, pyrafluprole,pyridalyl, pyriprole, sulfluramid, tetradifon, tetrasul, triarathene,verbutin, furthermore the compound 3-methylphenyl propylcarbamate(Tsumacide Z), the compound3-(5-chloro-3-pyridinyl)-8-(2,2,2-trifluoroethyl)-8-azabicyclo[3.2.1]octane-3-carbonitrile(CAS reg. No. 185982-80-3) and the corresponding 3-endo isomer (CAS reg.No. 185984-60-5) (cf. WO 96/37494, WO 98/25923), and also preparationscomprising insecticidal effective plant extracts, nematodes, fungi orviruses. Suitable examples of fumigants include aluminium phosphide,methyl bromide and sulphuryl fluoride. Suitable examples of selectivefeeding inhibitors include cryolite, flonicamid and pymetrozine.Suitable examples of mite growth inhibitors include clofentezine,etoxazole and hexythiazox.

Preferably, the insecticide compound (b) is chosen as being abamectin,acephate, acetamiprid, acrinathrin, aldicarb, alpha-cypermethrin,beta-cyfluthrin, bifenthrin, carbaryl, carbofuran, chlorfenapyr,chlorfluazuron, chlorpyrifos-E, clothianidin, cyfluthrin, cypermethrin,cyromazine, deltamethrin, diflubenzuron, dinotefuran, emamectinbenzoate, ethiprole, fenpyroximate, fipronil, flonicamid, flubendiamide,flufenoxuron, gamma-cyhalothrin, hexaflumuron, imidacloprid, indoxacarb,L-cyhalothrin, lepimectin, lufenuron, methamidophos, methiocarb,methomyl, methoxyfenozide, milbemycin, nitenpyram, novaluron,profenofos, pymetrozine, rynaxapyr, spinosad, spirodiclofen,spiromesifen, spirotetramate, tebufenozide, tebufenozide, tebufenpyrad,tebufenpyrad, tebupirimphos, teflubenzuron, tefluthrin, thiacloprid,thiamethoxam, thiodicarb, triazophos triflumuron, imidaclothiz and(2E)-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3,5-dimethyl-N-nitro-1,3,5-triazinan-2-imine.More preferably, the insecticide compound (b) is chosen as beingabamectin, acetamiprid, aldicarb, beta-cyfluthrin, carbofuran,chlorpyrifos-E, clothianidin, cypermethrin, cyromazine, deltamethrin,diflubenzuron, emamectin benzoate, ethiprole, fipronil,gamma-cyhalothrin, imidacloprid, L-cyhalothrin, lufenuron, methiocarb,methoxyfenozide, pymetrozine, rynaxapyr, spinosad, spirodiclofen,spiromesifen, spirotetramate, tebufenozide, tebufenpyrad, tefluthrin,thiacloprid, thiamethoxam, thiodicarb, triflumuron, imidaclothiz and(2E)-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3,5-dimethyl-N-nitro-1,3,5-triazinan-2-imine.Even more preferably, the insecticide compound (b) is chosen as beingabamectin, aldicarb, beta-cyfluthrin, chlorpyrifos-E, clothianidin,cyromazine, deltamethrin, diflubenzuron, emamectin benzoate, fipronil,gamma-cyhalothrin, imidacloprid, L-cyhalothrin, methiocarb, pymetrozine,rynaxapyr, spinosad, spirodiclofen, spiromesifen, spirotetramate,tebufenozide, tebufenpyrad, tefluthrin, thiamethoxam, thiodicarb,imidaclothiz,(2E)-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3,5-dimethyl-N-nitro-1,3,5-triazinan-2-imine.

Non limitative examples of suitable mixtures according to the presentinvention may include mixtures of fenamidone with abamectin, fenamidonewith acephate, fenamidone with acetamiprid, fenamidone with acrinathrin,fenamidone with aldicarb, fenamidone with alpha-cypermethrin, fenamidonewith beta-cyfluthrin, fenamidone with bifenthrin, fenamidone withcarbaryl, fenamidone with carbofuran, fenamidone with chlorfenapyr,fenamidone with chlorfluazuron, fenamidone with chlorpyrifos-E,fenamidone with clothianidin, fenamidone with cyfluthrin, fenamidonewith cypermethrin, fenamidone with cyromazine, fenamidone withdeltamethrin, fenamidone with diflubenzuron, fenamidone withdinotefuran, fenamidone with emamectin benzoate, fenamidone withethiprole, fenamidone with fenpyroximate, fenamidone with fipronil,fenamidone with flonicamid, fenamidone with flubendiamide, fenamidonewith flufenoxuron, fenamidone with gamma-cyhalothrin, fenamidone withhexaflumuron, fenamidone with imidacloprid, fenamidone with indoxacarb,fenamidone with L-cyhalothrin, fenamidone with lepimectin, fenamidonewith lufenuron, fenamidone with methamidophos, fenamidone withmethiocarb, fenamidone with methomyl, fenamidone with methoxyfenozide,fenamidone with milbemycin, fenamidone with nitenpyram, fenamidone withnovaluron, fenamidone with profenofos, fenamidone with pymetrozine,fenamidone with rynaxapyr, fenamidone with spinosad, fenamidone withspirodiclofen, fenamidone with spiromesifen, fenamidone withspirotetramate, fenamidone with tebufenozide, fenamidone withtebufenozide, fenamidone with tebufenpyrad, fenamidone withtebufenpyrad, fenamidone with tebupirimphos, fenamidone withteflubenzuron, fenamidone with tefluthrin, fenamidone with thiacloprid,fenamidone with thiamethoxam, fenamidone with thiodicarb, fenamidonewith triazophos, fenamidone with triflumuron, fenamidone withimidaclothiz and fenamidone with(2E)-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3,5-dimethyl-N-nitro-1,3,5-triazinan-2-imine.

The composition according to the present invention comprises a compoundof general formula (I) (a) and an insecticide compound (b) in asynergistically effective weight ratio of a:b of from 1/1000 to 1000/1.Preferably, (a)/(b) weight ratio is of from 1/125 to 125/1. Even morepreferably, (a)/(b) weight ratio is of from 1/25 to 25/1.

Furthermore in the combinations according to the invention the compoundsA and B are present in a synergistically effective weight ratio of A:Bin a range of 100:1 to 1:50, 100:1 to 1:20, 50:1 to 1:100, 50:1 to 1:20,20:1 to 1:100, 20:1 to 1:50. Further ratios of A:B which can be usedaccording to the present invention with increasing preference in theorder given are: 95:1 to 1:95, 95:1 to 1:90, 95:1 to 1:85, 95:1 to 1:80,95:1 to 1:75, 95:1 to 1:70, 95:1 to 1:65, 95:1 to 1:60, 95:1 to 1:55,95:1 to 1:50, 95:1 to 1:45, 95:1 to 1:40, 95:1 to 1:35, 95:1 to 1:30,95:1 to 1:25, 95:1 to 1:20, 95:1 to 1:15, 95:1 to 1:10, 95:1 to 1:5,95:1 to 1:4, 95:1 to 1:3, 95:1 to 1:2, 90:1 to 1:90, 90:1 to 1:95, 90:1to 1:85, 90:1 to 1:80, 90:1 to 1:75, 90:1 to 1:70, 90:1 to 1:65, 90:1 to1:60, 90:1 to 1:55, 90:1 to 1:50, 90:1 to 1:45, 90:1 to 1:40, 90:1 to1:35, 90:1 to 1:30, 90:1 to 1:25, 90:1 to 1:20, 90:1 to 1:15, 90:1 to1:10, 90:1 to 1:5, 90:1 to 1:4, 90:1 to 1:3, 90:1 to 1:2, 85:1 to 1:85,85:1 to 1:95, 85:1 to 1:90, 85:1 to 1:80, 85:1 to 1:75, 85:1 to 1:70,85:1 to 1:65, 85:1 to 1:60, 85:1 to 1:55, 85:1 to 1:50, 85:1 to 1:45,85:1 to 1:40, 85:1 to 1:35, 85:1 to 1:30, 85:1 to 1:25, 85:1 to 1:20,85:1 to 1:15, 85:1 to 1:10, 85:1 to 1:5, 85:1 to 1:4, 85:1 to 1:3, 85:1to 1:2, 80:1 to 1:80, 80:1 to 1:95, 80:1 to 1:90, 80:1 to 1:85, 80:1 to1:75, 80:1 to 1:70, 80:1 to 1:65, 80:1 to 1:60, 80:1 to 1:55, 80:1 to1:50, 80:1 to 1:45, 80:1 to 1:40, 80:1 to 1:35, 80:1 to 1:30, 80:1 to1:25, 80:1 to 1:20, 80:1 to 1:15, 80:1 to 1:10, 80:1 to 1:5, 80:1 to1:4, 80:1 to 1:3, 80:1 to 1:2, 75:1 to 1:75, 75:1 to 1:95, 75:1 to 1:90,75:1 to 1:85, 75:1 to 1:80, 75:1 to 1:70, 75:1 to 1:65, 75:1 to 1:60,75:1 to 1:55, 75:1 to 1:50, 75:1 to 1:45, 75:1 to 1:40, 75:1 to 1:35,75:1 to 1:30, 75:1 to 1:25, 75:1 to 1:20, 75:1 to 1:15, 75:1 to 1:10,75:1 to 1:5, 75:1 to 1:4, 75:1 to 1:3, 75:1 to 1:2, 70:1 to 1:70, 70:1to 1:95, 70:1 to 1:90, 70:1 to 1:85, 70:1 to 1:80, 70:1 to 1:75, 70:1 to1:65, 70:1 to 1:60, 70:1 to 1:55, 70:1 to 1:50, 70:1 to 1:45, 70:1 to1:40, 70:1 to 1:35, 70:1 to 1:30, 70:1 to 1:25, 70:1 to 1:20, 70:1 to1:15, 70:1 to 1:10, 70:1 to 1:5, 70:1 to 1:4, 70:1 to 1:3, 70:1 to 1:2,65:1 to 1:65, 65:1 to 1:95, 65:1 to 1:90, 65:1 to 1:85, 65:1 to 1:80,65:1 to 1:75, 65:1 to 1:70, 65:1 to 1:60, 65:1 to 1:55, 65:1 to 1:50,65:1 to 1:45, 65:1 to 1:40, 65:1 to 1:35, 65:1 to 1:30, 65:1 to 1:25,65:1 to 1:20, 65:1 to 1:15, 65:1 to 1:10, 65:1 to 1:5, 65:1 to 1:4, 65:1to 1:3, 65:1 to 1:2, 60:1 to 1:60, 60:1 to 1:95, 60:1 to 1:90, 60:1 to1:85, 60:1 to 1:80, 60:1 to 1:75, 60:1 to 1:70, 60:1 to 1:65, 60:1 to1:55, 60:1 to 1:50, 60:1 to 1:45, 60:1 to 1:40, 60:1 to 1:35, 60:1 to1:30, 60:1 to 1:25, 60:1 to 1:20, 60:1 to 1:15, 60:1 to 1:10, 60:1 to1:5, 60:1 to 1:4, 60:1 to 1:3, 60:1 to 1:2, 55:1 to 1:55, 55:1 to 1:95,55:1 to 1:90, 55:1 to 1:85, 55:1 to 1:80, 55:1 to 1:75, 55:1 to 1:70,55:1 to 1:65, 55:1 to 1:60, 55:1 to 1:50, 55:1 to 1:45, 55:1 to 1:40,55:1 to 1:35, 55:1 to 1:30, 55:1 to 1:25, 55:1 to 1:20, 55:1 to 1:15,55:1 to 1:10, 55:1 to 1:5, 55:1 to 1:4, 55:1 to 1:3, 55:1 to 1:2, 50:1to 1:95, 50:1 to 1:90, 50:1 to 1:85, 50:1 to 1:80, 50:1 to 1:75, 50:1 to1:70, 50:1 to 1:65, 50:1 to 1:60, 50:1 to 1:55, 50:1 to 1:45, 50:1 to1:40, 50:1 to 1:35, 50:1 to 1:30, 50:1 to 1:25, 50:1 to 1:20, 50:1 to1:15, 50:1 to 1:10, 50:1 to 1:5, 50:1 to 1:4, 50:1 to 1:3, 50:1 to 1:2,45:1 to 1:45, 45:1 to 1:95, 45:1 to 1:90, 45:1 to 1:85, 45:1 to 1:80,45:1 to 1:75, 45:1 to 1:70, 45:1 to 1:65, 45:1 to 1:60, 45:1 to 1:55,45:1 to 1:50, 45:1 to 1:40, 45:1 to 1:35, 45:1 to 1:30, 45:1 to 1:25,45:1 to 1:20, 45:1 to 1:15, 45:1 to 1:10, 45:1 to 1:5, 45:1 to 1:4, 45:1to 1:3, 45:1 to 1:2, 40:1 to 1:40, 40:1 to 1:95, 40:1 to 1:90, 40:1 to1:85, 40:1 to 1:80, 40:1 to 1:75, 40:1 to 1:70, 40:1 to 1:65, 40:1 to1:60, 40:1 to 1:55, 40:1 to 1:50, 40:1 to 1:45, 40:1 to 1:35, 40:1 to1:30, 40:1 to 1:25, 40:1 to 1:20, 40:1 to 1:15, 40:1 to 1:10, 40:1 to1:5, 40:1 to 1:4, 40:1 to 1:3, 40:1 to 1:2, 35:1 to 1:35, 35:1 to 1:95,35:1 to 1:90, 35:1 to 1:85, 35:1 to 1:80, 35:1 to 1:75, 35:1 to 1:70,35:1 to 1:65, 35:1 to 1:60, 35:1 to 1:55, 35:1 to 1:50, 35:1 to 1:45,35:1 to 1:40, 35:1 to 1:30, 35:1 to 1:25, 35:1 to 1:20, 35:1 to 1:15,35:1 to 1:10, 35:1 to 1:5, 35:1 to 1:4, 35:1 to 1:3, 35:1 to 1:2, 30:1to 1:30, 30:1 to 1:95, 30:1 to 1:90, 30:1 to 1:85, 30:1 to 1:80, 30:1 to1:75, 30:1 to 1:70, 30:1 to 1:65, 30:1 to 1:60, 30:1 to 1:55, 30:1 to1:50, 30:1 to 1:45, 30:1 to 1:40, 30:1 to 1:35, 30:1 to 1:25, 30:1 to1:20, 30:1 to 1:15, 30:1 to 1:10, 30:1 to 1:5, 30:1 to 1:4, 30:1 to 1:3,30:1 to 1:2, 25:1 to 1:25, 25:1 to 1:95, 25:1 to 1:90, 25:1 to 1:85,25:1 to 1:80, 25:1 to 1:75, 25:1 to 1:70, 25:1 to 1:65, 25:1 to 1:60,25:1 to 1:55, 25:1 to 1:50, 25:1 to 1:45, 25:1 to 1:40, 25:1 to 1:35,25:1 to 1:30, 25:1 to 1:20, 25:1 to 1:15, 25:1 to 1:10, 25:1 to 1:5,25:1 to 1:4, 25:1 to 1:3, 25:1 to 1:2, 20:1 to 1:95, 20:1 to 1:90, 20:1to 1:85, 20:1 to 1:80, 20:1 to 1:75, 20:1 to 1:70, 20:1 to 1:65, 20:1 to1:60, 20:1 to 1:55, 20:1 to 1:50, 20:1 to 1:45, 20:1 to 1:40, 20:1 to1:35, 20:1 to 1:30, 20:1 to 1:25, 20:1 to 1:15, 20:1 to 1:10, 20:1 to1:5, 20:1 to 1:4, 20:1 to 1:3, 20:1 to 1:2, 15:1 to 1:15, 15:1 to 1:95,15:1 to 1:90, 15:1 to 1:85, 15:1 to 1:80, 15:1 to 1:75, 15:1 to 1:70,15:1 to 1:65, 15:1 to 1:60, 15:1 to 1:55, 15:1 to 1:50, 15:1 to 1:45,15:1 to 1:40, 15:1 to 1:35, 15:1 to 1:30, 15:1 to 1:25, 15:1 to 1:20,15:1 to 1:10, 15:1 to 1:5, 15:1 to 1:4, 15:1 to 1:3, 15:1 to 1:2, 10:1to 1:10, 10:1 to 1:95, 10:1 to 1:90, 10:1 to 1:85, 10:1 to 1:80, 10:1 to1:75, 10:1 to 1:70, 10:1 to 1:65, 10:1 to 1:60, 10:1 to 1:55, 10:1 to1:50, 10:1 to 1:45, 10:1 to 1:40, 10:1 to 1:35, 10:1 to 1:30, 10:1 to1:25, 10:1 to 1:20, 10:1 to 1:15, 10:1 to 1:5, 10:1 to 1:4, 10:1 to 1:3,10:1 to 1:2, 5:1 to 1:5, 5:1 to 1:95, 5:1 to 1:90, 5:1 to 1:85, 5:1 to1:80, 5:1 to 1:75, 5:1 to 1:70, 5:1 to 1:65, 5:1 to 1:60, 5:1 to 1:55,5:1 to 1:50, 5:1 to 1:45, 5:1 to 1:40, 5:1 to 1:35, 5:1 to 1:30, 5:1 to1:25, 5:1 to 1:20, 5:1 to 1:15, 5:1 to 1:10, 5:1 to 1:4, 5:1 to 1:3, 5:1to 1:2, 4:1 to 1:4, 4:1 to 1:95, 4:1 to 1:90, 4:1 to 1:85, 4:1 to 1:80,4:1 to 1:75, 4:1 to 1:70, 4:1 to 1:65, 4:1 to 1:60, 4:1 to 1:55, 4:1 to1:50, 4:1 to 1:45, 4:1 to 1:40, 4:1 to 1:35, 4:1 to 1:30, 4:1 to 1:25,4:1 to 1:20, 4:1 to 1:15, 4:1 to 1:10, 4:1 to 1:5, 4:1 to 1:3, 4:1 to1:2, 3:1 to 1:3, 3:1 to 1:95, 3:1 to 1:90, 3:1 to 1:85, 3:1 to 1:80, 3:1to 1:75, 3:1 to 1:70, 3:1 to 1:65, 3:1 to 1:60, 3:1 to 1:55, 3:1 to1:50, 3:1 to 1:45, 3:1 to 1:40, 3:1 to 1:35, 3:1 to 1:30, 3:1 to 1:25,3:1 to 1:20, 3:1 to 1:15, 3:1 to 1:10, 3:1 to 1:5, 3:1 to 1:4, 3:1 to1:2, 2:1 to 1:2, 2:1 to 1:95, 2:1 to 1:90, 2:1 to 1:85, 2:1 to 1:80, 2:1to 1:75, 2:1 to 1:70, 2:1 to 1:65, 2:1 to 1:60, 2:1 to 1:55, 2:1 to1:50, 2:1 to 1:45, 2:1 to 1:40, 2:1 to 1:35, 2:1 to 1:30, 2:1 to 1:25,2:1 to 1:20, 2:1 to 1:15, 2:1 to 1:10, 2:1 to 1:5, 2:1 to 1:4, 2:1 to1:3.

The composition of the present invention may further comprise at leastone other different fungicide active ingredient (c).

Examples of suitable fungicide mixing partners may be selected in thefollowing lists:

c1) a compound capable to inhibit the nucleic acid synthesis likebenalaxyl, benalaxyl-M, bupirimate, chiralaxyl, clozylacon,dimethirimol, ethirimol, furalaxyl, hymexazol, mefenoxam, metalaxyl,metalaxyl-M, ofurace, oxadixyl, oxolinic acid;c2) a compound capable to inhibit the mitosis and cell division likebenomyl, carbendazim, diethofencarb, ethaboxam, fuberidazole,pencycuron, thiabendazole thiophanate-methyl, zoxamide;c3) a compound capable to inhibit the respiration for exampleas CI-respiration inhibitor like diflumetorim;as CII-respiration inhibitor like boscalid, carboxin, fenfuram,flutolanil, furametpyr, furmecyclox, mepronil, oxycarboxine,penthiopyrad, thifluzamide;as CIII-respiration inhibitor like amisulbrom, azoxystrobin, cyazofamid,dimoxystrobin, enestrobin, famoxadone, fenamidone, fluoxastrobin,kresoxim-methyl, metominostrobin, orysastrobin, picoxystrobin,pyraclostrobin, trifloxystrobin;c4) a compound capable of to act as an uncoupler like dinocap,fluazinam, meptyldinocap;c5) a compound capable to inhibit ATP production like fentin acetate,fentin chloride, fentin hydroxide, silthiofam;c6) a compound capable to inhibit AA and protein biosynthesis likeandoprim, blasticidin-S, cyprodinil, kasugamycin, kasugamycinhydrochloride hydrate, mepanipyrim, pyrimethanil;c7) a compound capable to inhibit the signal transduction likefenpiclonil, fludioxonil, quinoxyfen;c8) a compound capable to inhibit lipid and membrane synthesis likebiphenyl, chlozolinate, edifenphos, etridiazole, iodocarb, iprobenfos,iprodione, isoprothiolane, procymidone, propamocarb, propamocarbhydrochloride, pyrazophos, tolclofos-methyl, vinclozolin;c9) a compound capable to inhibit ergosterol biosynthesis likealdimorph, azaconazole, bitertanol, bromuconazole, cyproconazole,diclobutrazole, difenoconazole, diniconazole, diniconazole-M, dodemorph,dodemorph acetate, epoxiconazole, etaconazole, fenarimol, fenbuconazole,fenhexamid, fenpropidin, fenpropimorph, fluquinconazole, flurprimidol,flusilazole, flutriafol, furconazole, furconazole-cis, hexaconazole,imazalil, imazalil sulfate, imibenconazole, ipconazole, metconazole,myclobutanil, naftifine, nuarimol, oxpoconazole, paclobutrazol,pefurazoate, penconazole, prochloraz, propiconazole, prothioconazole,pyributicarb, pyrifenox, simeconazole, spiroxamine, tebuconazole,terbinafine, tetraconazole, triadimefon, triadimenol, tridemorph,triflumizole, triforine, triticonazole, uniconazole, viniconazole,voriconazole;c10) a compound capable to inhibit cell wall synthesis likebenthiavalicarb, bialaphos, dimethomorph, flumorph, iprovalicarb,mandipropamid, polyoxins, polyoxorim, validamycin A;c11) a compound capable to inhibit melanine biosynthesis likecarpropamid, diclocymet, fenoxanil, phthalide, pyroquilon, tricyclazole;c12) a compound capable to induce a host defence likeacibenzolar-5-methyl, probenazole, tiadinil;c13) a compound capable to have a multisite action like Bordeauxmixture, captafol, captan, chlorothalonil, copper naphthenate, copperoxide, copper oxychloride, copper preparations such as copper hydroxide,copper sulphate, dichlofluanid, dithianon, dodine, dodine free base,ferbam, fluorofolpet, folpet, guazatine, guazatine acetate,iminoctadine, iminoctadine albesilate, iminoctadine triacetate,mancopper, mancozeb, maneb, metiram, metiram zinc, oxine-copper,propineb, sulphur and sulphur preparations including calciumpolysulphide, thiram, tolylfluanid, zineb, ziram;c14) a compound selected in the following list:(2E)-2-(2-{[6-(3-chloro-2-methylphenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)-2-(methoxyimino)-N-methylacetamide,(2E)-2-{2-[({[(1E)-1-(3-{[(E)-1-fluoro-2-phenylvinyl]oxy}phenyl)ethylidene]amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide,1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)cycloheptanol,1-[(4-methoxyphenoxy)methyl]-2,2-dimethylpropyl-1H-imidazole-1-carboxylate,2,3,5,6-tetrachloro-4-(methylsulfonyl)pyridine,2-butoxy-6-iodo-3-propyl-4H-chromen-4-one,2-chloro-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)nicotinamide,2-phenylphenol and salts, 3,4,5-trichloropyridine-2,6-dicarbonitrile,3,4-dichloro-N-(2-cyanophenyl)isothiazole-5-carboxamide,3-[5-(4-chlorophenyl)-2,3-dimethylisoxazolidin-3-yl]pyridine,5-chloro-6-(2,4,6-trifluorophenyl)-N-[(1R)-1,2,2-trimethylpropyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine,5-chloro-7-(4-methylpiperidin-1-yl)-6-(2,4,6-trifluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine,5-chloro-N-[(1R)-1,2-dimethylpropyl]-6-(2,4,6-trifluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine,8-hydroxyquinoline sulfate, benthiazole, bethoxazin, capsimycin,carvone, chinomethionat, cufraneb, cyflufenamid, cymoxanil, dazomet,debacarb, dichlorophen, diclomezine, dicloran, difenzoquat, difenzoquatmethylsulphate, diphenylamine, ferimzone, flumetover, fluopicolide,fluoroimide, flusulfamide, fosetyl-aluminium, fosetyl-calcium,fosetyl-sodium, hexachlorobenzene, irumamycin, isotianil,methasulfocarb, methyl(2E)-2-{2-[({cyclopropyl[(4-methoxyphenyl)imino]methyl}thio)methyl]phenyl}-3-methoxyacrylate,methyl1-(2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)-1H-imidazole-5-carboxylate,methyl isothiocyanate, metrafenone, mildiomycin,N-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide,N-(3′,4′-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide,N-(3-ethyl-3,5,5-trimethylcyclohexyl)-3-(formylamino)-2-hydroxybenzamide,N-(4-chloro-2-nitrophenyl)-N-ethyl-4-methylbenzenesulfonamide,N-(4-chlorobenzyl)-3-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]propanamide,N-[(4-chlorophenyl)(cyano)methyl]-3-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]propanamide,N-[(5-bromo-3-chloropyridin-2-yl)methyl]-2,4-dichloronicotinamide,N-[1-(5-bromo-3-chloropyridin-2-yl)ethyl]-2,4-dichloronicotinamide,N-[1-(5-bromo-3-chloropyridin-2-yl)ethyl]-2-fluoro-4-iodonicotinamide,N-[2-(4-{[3-(4-chloro-phenyl)prop-2-yn-1-yl]oxy}-3-methoxyphenyl)ethyl]-N<-(methylsulfonyl)valinamide,N-{(Z)-[(Cyclopropylmethoxy)imino][6-(difluoromethoxy)-2,3-difluorophenyl]methyl}-2-phenyl-acetamide,N-{2-[1,1′-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-,1-methyl-1H-pyrazole-4-carboxamide,N-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl}-2-(trifluoromethyl)benzamide,natamycin,N-ethyl-N-methyl-N′-{2-methyl-5-(trifluoromethyl)-4-[3-(trimethylsilyl)propoxy]phenyl}imidoformamide,N-ethyl-N-methyl-N′-{2-methyl-5-(difluoromethyl)-4-[3-(trimethylsilyl)propoxy]phenyl}imidoformamide,nickel dimethyldithiocarbamate, nitrothal-isopropyl,0-{1-[(4-methoxyphenoxy)methyl]-2,2-dimethylpropyl}1H-imidazole-1-carbothioate,octhilinone, oxamocarb, oxyfenthiin, pentachlorophenol and salts,phosphorous acid and its salts, piperalin, propamocarb fosetylate,propanosine-sodium, proquinazid, pyribencarb, pyrrolnitrine, quintozene,tecloftalam, tecnazene, triazoxide, trichlamide, valiphenal, zarilamid.

Preferably, fungicidal active ingredient (c) is selected from5-fluoro-1,3-dimethyl-N-[2-(1,3-dimethyl)-but-2-ol-yl]-1H-pyrazole-4-carboxamide,N-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide,benalaxyl, benalaxyl-M, benthiavalicarb, carboxin, chlorothalonil,cyazofamid, cymoxanil, dimetomorph, fluazinam, fludioxonil,fluquinconazole, fluoxastrobin, flutriafol, fosetyl-aluminium,hexaconazole, hymexazole, ipconazole, mancozeb, mandipropamid, maneb,mefenoxam, metiram, metalaxyl, metalaxyl-M, peconazole, penthiopyrad,phosphorous acid, propamocarb.HCl, propineb, prothioconazole,tebuconazole, thiram, triadimenol, trifloxystrobin and triticonazole.

Where the third active ingredient (c) as defined above is present in thecomposition, this compound may be present in an amount of (a):(b):(c)weight ratio of from 1:0.001:0.001 to 1:1000:1000; the ratios ofcompound (a) and compound (c) varying independently from each other.Preferably, the (a):(b):(c) weight ratio may be of from 1:0.01:0.01 to1:100:100. More preferably, the (a):(b):(c) weight ratio may be of from1:0.05:0.05 to 1:80:80.

Following compositions may be cited to illustrate in a non-limitedmanner the present invention: fenamidone withN-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide,and clothianidin, fenamidone with benalaxyl and clothianidin, fenamidonewith benalaxyl-M and clothianidin, fenamidone with benthiavalicarb andclothianidin, fenamidone with carboxin and clothianidin, fenamidone withchlorothalonil and clothianidin, fenamidone with cyazofamid andclothianidin, fenamidone with cymoxanil and clothianidin, fenamidonewith dimetomorph and clothianidin, fenamidone with fluazinam andclothianidin, fenamidone with fludioxonil and clothianidin, fenamidonewith fluquinconazole and clothianidin, fenamidone with fluoxastrobin andclothianidin, fenamidone with flutriafol and clothianidin, fenamidonewith fosetyl-aluminium and clothianidin, fenamidone with hexaconazoleand clothianidin, fenamidone with hymexazole and clothianidin,fenamidone with ipconazole and clothianidin, fenamidone with mancozeband clothianidin, fenamidone with mandipropamid and clothianidin,fenamidone with maneb and clothianidin, fenamidone with mefenoxam andclothianidin, fenamidone with metiram and clothianidin, fenamidone withmetalaxyl and clothianidin, fenamidone with metalaxyl-M andclothianidin, fenamidone with peconazole and clothianidin, fenamidonewith penthiopyrad and clothianidin, fenamidone with phosphorous acid andclothianidin, fenamidone with propamocarb.HCl and clothianidin,fenamidone with propineb and clothianidin, fenamidone withprothioconazole and clothianidin, fenamidone with tebuconazole andclothianidin, fenamidone with thiram and clothianidin, fenamidone withtriadimenol and clothianidin, fenamidone with trifloxystrobin andclothianidin, fenamidone with triticonazole and clothianidin, fenamidonewithN-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamideand imidacloprid, fenamidone with benalaxyl and imidacloprid, fenamidonewith benalaxyl-M and imidacloprid, fenamidone with benthiavalicarb andimidacloprid, fenamidone with carboxin and imidacloprid, fenamidone withchlorothalonil and imidacloprid, fenamidone with cyazofamid andimidacloprid, fenamidone with cymoxanil and imidacloprid, fenamidonewith dimetomorph and imidacloprid, fenamidone with fluazinam andimidacloprid, fenamidone with fludioxonil and imidacloprid, fenamidonewith fluquinconazole and imidacloprid, fenamidone with fluoxastrobin andimidacloprid, fenamidone with flutriafol and imidacloprid, fenamidonewith fosetyl-aluminium and imidacloprid, fenamidone with hexaconazoleand imidacloprid, fenamidone with hymexazole and imidacloprid,fenamidone with ipconazole and imidacloprid, fenamidone with mancozeband imidacloprid, fenamidone with mandipropamid and imidacloprid,fenamidone with maneb and imidacloprid, fenamidone with mefenoxam andimidacloprid, fenamidone with metiram and imidacloprid, fenamidone withmetalaxyl and imidacloprid, fenamidone with metalaxyl-M andimidacloprid, fenamidone with peconazole and imidacloprid, fenamidonewith penthiopyrad and imidacloprid, fenamidone with phosphorous acid andimidacloprid, fenamidone with propamocarb.HCl and imidacloprid,fenamidone with propineb and imidacloprid, fenamidone withprothioconazole and imidacloprid, fenamidone with tebuconazole andimidacloprid, fenamidone with thiram and imidacloprid, fenamidone withtriadimenol and imidacloprid, fenamidone with trifloxystrobin andimidacloprid, fenamidone with triticonazole and imidacloprid, fenamidonewith5-fluoro-1,3-dimethyl-N-[2-(1,3-dimethyl)-but-2-ol-yl]-1H-pyrazole-4-carboxamideand thiametoxam, fenamidone with benalaxyl and thiametoxam, fenamidonewith benalaxyl-M and thiametoxam, fenamidone with benthiavalicarb andthiametoxam, fenamidone with carboxin and thiametoxam, fenamidone withchlorothalonil and thiametoxam, fenamidone with cyazofamid andthiametoxam, fenamidone with cymoxanil and thiametoxam, fenamidone withdimetomorph and thiametoxam, fenamidone with fluazinam and thiametoxam,fenamidone with fludioxonil and thiametoxam, fenamidone withfluquinconazole and thiametoxam, fenamidone with fluoxastrobin andthiametoxam, fenamidone with flutriafol and thiametoxam, fenamidone withfosetyl-aluminium and thiametoxam, fenamidone with hexaconazole andthiametoxam, fenamidone with hymexazole and thiametoxam, fenamidone withipconazole and thiametoxam, fenamidone with mancozeb and thiametoxam,fenamidone with mandipropamid and thiametoxam, fenamidone with maneb andthiametoxam, fenamidone with mefenoxam and thiametoxam, fenamidone withmetiram and thiametoxam, fenamidone with metalaxyl and thiametoxam,fenamidone with metalaxyl-M and thiametoxam, fenamidone with peconazoleand thiametoxam, fenamidone with penthiopyrad and thiametoxam,fenamidone with phosphorous acid and thiametoxam, fenamidone withpropamocarb.HCl and thiametoxam, fenamidone with propineb andthiametoxam, fenamidone with prothioconazole and thiametoxam, fenamidonewith tebuconazole and thiametoxam, fenamidone with thiram andthiametoxam, fenamidone with triadimenol and thiametoxam, fenamidonewith trifloxystrobin and thiametoxam and fenamidone with triticonazoleand thiametoxam.

The composition according to the present invention may further comprisean other additional component such as an agriculturally acceptablesupport, carrier or filler.

In the present specification, the term “support” denotes a natural orsynthetic, organic or inorganic material with which the active materialis combined to make it easier to apply, notably to the parts of theplant. This support is thus generally inert and should be agriculturallyacceptable. The support may be a solid or a liquid. Examples of suitablesupports include clays, natural or synthetic silicates, silica, resins,waxes, solid fertilisers, water, alcohols, in particular butanol,organic solvents, mineral and plant oils and derivatives thereof.Mixtures of such supports may also be used.

The composition may also comprise other additional components. Inparticular, the composition may further comprise a surfactant. Thesurfactant can be an emulsifier, a dispersing agent or a wetting agentof ionic or non-ionic type or a mixture of such surfactants. Mention maybe made, for example, of polyacrylic acid salts, lignosulphonic acidsalts, phenolsulphonic or naphthalenesulphonic acid salts,polycondensates of ethylene oxide with fatty alcohols or with fattyacids or with fatty amines, substituted phenols (in particularalkylphenols or arylphenols), salts of sulphosuccinic acid esters,taurine derivatives (in particular alkyl taurates), phosphoric esters ofpolyoxyethylated alcohols or phenols, fatty acid esters of polyols, andderivatives of the above compounds containing sulphate, sulphonate andphosphate functions. The presence of at least one surfactant isgenerally essential when the active material and/or the inert supportare water-insoluble and when the vector agent for the application iswater. Preferably, surfactant content may be comprised between 5% and40% by weight of the composition.

Additional components may also be included, e.g. protective colloids,adhesives, thickeners, thixotropic agents, penetration agents,stabilisers, sequestering agents. More generally, the active materialscan be combined with any solid or liquid additive, which complies withthe usual formulation techniques.

In general, the composition according to the invention may contain from0.05 to 99% (by weight) of active material, preferably 10 to 70% byweight.

Compositions according to the present invention can be used in variousforms such as aerosol dispenser, capsule suspension, cold foggingconcentrate, dustable powder, emulsifiable concentrate, emulsion oil inwater, emulsion water in oil, encapsulated granule, fine granule,flowable concentrate for seed treatment, gas (under pressure), gasgenerating product, granule, hot fogging concentrate, macrogranule,microgranule, oil dispersible powder, oil miscible flowable concentrate,oil miscible liquid, paste, plant rodlet, powder for dry seed treatment,seed coated with a pesticide, soluble concentrate, soluble powder,solution for seed treatment, suspension concentrate (flowableconcentrate), ultra low volume (ulv) liquid, ultra low volume (ulv)suspension, water dispersible granules or tablets, water dispersiblepowder for slurry treatment, water soluble granules or tablets, watersoluble powder for seed treatment and wettable powder.

These compositions include not only compositions which are ready to beapplied to the plant or seed to be treated by means of a suitabledevice, such as a spraying or dusting device, but also concentratedcommercial compositions which must be diluted before they are applied tothe crop.

The pesticidal compositions of the present invention can be used tocuratively or preventively control phytopathogenic fungi of crops butalso to curatively or preventively control insects.

Thus, according to a further aspect of the present invention, there isprovided a method for preventively or curatively controllingphytopathogenic fungi of crops but also to curatively or preventivelycontrol insects characterised in that an effective and non-phytotoxicamount of a composition as hereinbefore defined is applied via seedtreatment, foliar application, stem application or drench/dripapplication (chemigation) to the seed, the plant and/or to the fruit ofthe plant or to soil and/or to inert substrate (e.g. inorganicsubstrates (e.g. sand, rockwool, glasswool, expanded minerals (e.g.perlite, vermiculite, zeolite, expanded clay)), Pumice, Pyroclasticmaterials/tuff, synthetic organic substrates (e.g. Polyurethane),organic substrates (e.g. peat, composts, tree waste products (e.g. coir,wood fibre/chips, tree bark)) and/or to a liquid substrate (e.g.floating hydroponic systems, Nutrient Film Technique, Aeroponics) inwhich the plant is growing or in which it is desired to grow.

The expression “effective and non-phytotoxic amount” means an amount ofcomposition according to the invention which is sufficient to control ordestroy the pests and/or diseases present or liable to appear on thecrops, and which does not entail any appreciable symptom ofphytotoxicity for the said crops. Such an amount can vary within a widerange depending on the pests and diseases to be combated or controlled,the type of crop, the climatic conditions and the compounds included inthe composition according to the invention.

This amount can be determined by systematic field trials, which arewithin the capabilities of a person skilled in the art.

The method of treatment according to the present invention is useful totreat propagation material such as tubers or rhizomes, but also seeds,seedlings or seedlings pricking out and plants or plants pricking out.This method of treatment can also be useful to treat roots. The methodof treatment according to the present invention can also be useful totreat the overground parts of the plant such as trunks, stems or stalks,leaves, flowers and fruits of the concerned plant.

Among the plants that can be protected by the method according to thepresent invention, mention may be made of cotton; flax; vine; fruit orvegetable crops such as Rosaceae sp. (for instance pip fruit such asapples and pears, but also stone fruit such as apricots, almonds andpeaches), Ribesioidae sp., Juglandaceae sp., Betulaceae sp.,Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae sp.,Actimidaceae sp., Lauraceae sp., Musaceae sp. (for instance banana treesand plantins), Rubiaceae sp., Theaceae sp., Sterculiceae sp., Rutaceaesp. (for instance lemons, oranges and grapefruit); Solanaceae sp. (forinstance tomatoes), Liliaceae sp., Asteraceae sp. (for instancelettuces), Umbelliferae sp., Cruciferae sp., Chenopodiaceae sp.,Cucurbitaceae sp., Papilionaceae sp. (for instance peas), Rosaceae sp.(for instance strawberries); major crops such as Graminae sp. (forinstance maize, lawn or cereals such as wheat, rice, barley andtriticale), Asteraceae sp. (for instance sunflower), Cruciferae sp. (forinstance colza), Fabacae sp. (for instance peanuts), Papilionaceae sp.(for instance soybean), Solanaceae sp. (for instance potatoes),Chenopodiaceae sp. (for instance beetroots); horticultural and forestcrops; as well as genetically modified homologues of these crops.

The method of treatment according to the invention can be used in thetreatment of genetically modified organisms (GMOs), e.g. plants orseeds. Genetically modified plants (or transgenic plants) are plants inwhich a heterologous gene has been stably integrated into the genome.The expression “heterologous gene” essentially means a gene which isprovided or assembled outside the plant and when introduced in thenuclear, chloroplastic or mitochondrial genome gives the transformedplant new or improved agronomic or other properties by expressing aprotein or polypeptide of interest or by downregulating or silencingother gene(s) which are present in the plant (using for example,antisense technology, co suppression technology or RNAinterference—RNAi—technology). A heterologous gene that is located inthe genome is also called a transgene. A transgene that is defined byits particular location in the plant genome is called a transformationor transgenic event.

Depending on the plant species or plant cultivars, their location andgrowth conditions (soils, climate, vegetation period, diet), thetreatment according to the invention may also result in superadditive(“synergistic”) effects. Thus, for example, reduced application ratesand/or a widening of the activity spectrum and/or an increase in theactivity of the active compounds and compositions which can be usedaccording to the invention, better plant growth, increased tolerance tohigh or low temperatures, increased tolerance to drought or to water orsoil salt content, increased flowering performance, easier harvesting,accelerated maturation, higher harvest yields, bigger fruits, largerplant height, greener leaf color, earlier flowering, higher qualityand/or a higher nutritional value of the harvested products, highersugar concentration within the fruits, better storage stability and/orprocessability of the harvested products are possible, which exceed theeffects which were actually to be expected.

At certain application rates, the active compound combinations accordingto the invention may also have a strengthening effect in plants.Accordingly, they are also suitable for mobilizing the defense system ofthe plant against attack by unwanted phytopathogenic fungi and/ormicroorganisms and/or viruses. This may, if appropriate, be one of thereasons of the enhanced activity of the combinations according to theinvention, for example against fungi. Plant-strengthening(resistance-inducing) substances are to be understood as meaning, in thepresent context, those substances or combinations of substances whichare capable of stimulating the defense system of plants in such a waythat, when subsequently inoculated with unwanted phytopathogenic fungiand/or microorganisms and/or viruses, the treated plants display asubstantial degree of resistance to these unwanted phytopathogenic fungiand/or microorganisms and/or viruses. In the present case, unwantedphytopathogenic fungi and/or microorganisms and/or viruses are to beunderstood as meaning phytopathogenic fungi, bacteria and viruses. Thus,the substances according to the invention can be employed for protectingplants against attack by the abovementioned pathogens within a certainperiod of time after the treatment. The period of time within whichprotection is effected generally extends from 1 to 10 days, preferably 1to 7 days, after the treatment of the plants with the active compounds.

Plants and plant cultivars which are preferably to be treated accordingto the invention include all plants which have genetic material whichimpart particularly advantageous, useful traits to these plants (whetherobtained by breeding and/or biotechnological means).

Plants and plant cultivars which are also preferably to be treatedaccording to the invention are resistant against one or more bioticstresses, i.e. said plants show a better defense against animal andmicrobial pests, such as against nematodes, insects, mites,phytopathogenic fungi, bacteria, viruses and/or viroids.

Plants and plant cultivars which may also be treated according to theinvention are those plants which are resistant to one or more abioticstresses. Abiotic stress conditions may include, for example, drought,cold temperature exposure, heat exposure, osmotic stress, flooding,increased soil salinity, increased mineral exposure, ozon exposure, highlight exposure, limited availability of nitrogen nutrients, limitedavailability of phosphorus nutrients, shade avoidance.

Plants and plant cultivars which may also be treated according to theinvention, are those plants characterized by enhanced yieldcharacteristics. Increased yield in said plants can be the result of,for example, improved plant physiology, growth and development, such aswater use efficiency, water retention efficiency, improved nitrogen use,enhanced carbon assimilation, improved photosynthesis, increasedgermination efficiency and accelerated maturation. Yield can furthermorebe affected by improved plant architecture (under stress and non-stressconditions), including but not limited to, early flowering, floweringcontrol for hybrid seed production, seedling vigor, plant size,internode number and distance, root growth, seed size, fruit size, podsize, pod or ear number, seed number per pod or ear, seed mass, enhancedseed filling, reduced seed dispersal, reduced pod dehiscence and lodgingresistance. Further yield traits include seed composition, such ascarbohydrate content, protein content, oil content and composition,nutritional value, reduction in anti-nutritional compounds, improvedprocessability and better storage stability.

Plants that may be treated according to the invention are hybrid plantsthat already express the characteristic of heterosis or hybrid vigorwhich results in generally higher yield, vigor, health and resistancetowards biotic and abiotic stress factors. Such plants are typicallymade by crossing an inbred male-sterile parent line (the female parent)with another inbred male-fertile parent line (the male parent). Hybridseed is typically harvested from the male sterile plants and sold togrowers. Male sterile plants can sometimes (e.g. in corn) be produced bydetasseling, i.e. the mechanical removal of the male reproductive organs(or males flowers) but, more typically, male sterility is the result ofgenetic determinants in the plant genome. In that case, and especiallywhen seed is the desired product to be harvested from the hybrid plantsit is typically useful to ensure that male fertility in the hybridplants is fully restored. This can be accomplished by ensuring that themale parents have appropriate fertility restorer genes which are capableof restoring the male fertility in hybrid plants that contain thegenetic determinants responsible for male-sterility. Geneticdeterminants for male sterility may be located in the cytoplasm.Examples of cytoplasmic male sterility (CMS) were for instance describedin Brassica species (WO 1992/005251, WO 1995/009910, WO 1998/27806, WO2005/002324, WO 2006/021972 and U.S. Pat. No. 6,229,072). However,genetic determinants for male sterility can also be located in thenuclear genome. Male sterile plants can also be obtained by plantbiotechnology methods such as genetic engineering. A particularly usefulmeans of obtaining male-sterile plants is described in WO 1989/10396 inwhich, for example, a ribonuclease such as bamase is selectivelyexpressed in the tapetum cells in the stamens. Fertility can then berestored by expression in the tapetum cells of a ribonuclease inhibitorsuch as barstar (e.g. WO 1991/002069).

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may be treated according to the inventionare herbicide-tolerant plants, i.e. plants made tolerant to one or moregiven herbicides. Such plants can be obtained either by genetictransformation, or by selection of plants containing a mutationimparting such herbicide tolerance.

Herbicide-tolerant plants are for example glyphosate-tolerant plants,i.e. plants made tolerant to the herbicide glyphosate or salts thereof.Plants can be made tolerant to glyphosate through different means. Forexample, glyphosate-tolerant plants can be obtained by transforming theplant with a gene encoding the enzyme 5-enolpyruvylshikimate-3-phosphatesynthase (EPSPS). Examples of such EPSPS genes are the AroA gene (mutantCT7) of the bacterium Salmonella typhimurium (Comai et al., Science(1983), 221, 370-371), the CP4 gene of the bacterium Agrobacterium sp.(Barry et al., Curr. Topics Plant Physiol. (1992), 7, 139-145), thegenes encoding a Petunia EPSPS (Shah et al., Science (1986), 233,478-481), a Tomato EPSPS (Gasser et al., J. Biol. Chem. (1988), 263,4280-4289), or an Eleusine EPSPS (WO 2001/66704). It can also be amutated EPSPS as described in for example EP-A 0837944, WO 2000/066746,WO 2000/066747 or WO 2002/026995. Glyphosate-tolerant plants can also beobtained by expressing a gene that encodes a glyphosate oxido-reductaseenzyme as described in U.S. Pat. No. 5,776,760 and U.S. Pat. No.5,463,175. Glyphosate-tolerant plants can also be obtained by expressinga gene that encodes a glyphosate acetyl transferase enzyme as describedin for example WO 2002/036782, WO 2003/092360, WO 2005/012515 and WO2007/024782. Glyphosate-tolerant plants can also be obtained byselecting plants containing naturally-occurring mutations of theabove-mentioned genes, as described in for example WO 2001/024615 or WO2003/013226.

Other herbicide resistant plants are for example plants that are madetolerant to herbicides inhibiting the enzyme glutamine synthase, such asbialaphos, phosphinothricin or glufosinate. Such plants can be obtainedby expressing an enzyme detoxifying the herbicide or a mutant glutaminesynthase enzyme that is resistant to inhibition. One such efficientdetoxifying enzyme is an enzyme encoding a phosphinothricinacetyltransferase (such as the bar or pat protein from Streptomycesspecies). Plants expressing an exogenous phosphinothricinacetyltransferase are for example described in U.S. Pat. No. 5,561,236;U.S. Pat. No. 5,648,477; U.S. Pat. No. 5,646,024; U.S. Pat. No.5,273,894; U.S. Pat. No. 5,637,489; U.S. Pat. No. 5,276,268; U.S. Pat.No. 5,739,082; U.S. Pat. No. 5,908,810 and U.S. Pat. No. 7,112,665.

Further herbicide-tolerant plants are also plants that are made tolerantto the herbicides inhibiting the enzyme hydroxyphenylpyruvatedioxygenase(HPPD). Hydroxyphenylpyruvatedioxygenases are enzymes that catalyze thereaction in which para-hydroxyphenylpyruvate (HPP) is transformed intohomogentisate. Plants tolerant to HPPD-inhibitors can be transformedwith a gene encoding a naturally-occurring resistant HPPD enzyme, or agene encoding a mutated HPPD enzyme as described in WO 1996/038567, WO1999/024585 and WO 1999/024586. Tolerance to HPPD-inhibitors can also beobtained by transforming plants with genes encoding certain enzymesenabling the formation of homogentisate despite the inhibition of thenative HPPD enzyme by the HPPD-inhibitor. Such plants and genes aredescribed in WO 1999/034008 and WO 2002/36787. Tolerance of plants toHPPD inhibitors can also be improved by transforming plants with a geneencoding an enzyme prephenate dehydrogenase in addition to a geneencoding an HPPD-tolerant enzyme, as described in WO 2004/024928.

Still further herbicide resistant plants are plants that are madetolerant to acetolactate synthase (ALS) inhibitors. Known ALS-inhibitorsinclude, for example, sulfonylurea, imidazolinone, triazolopyrimidines,pyrimidinyloxy(thio)benzoates, and/or sulfonylaminocarbonyltriazolinoneherbicides. Different mutations in the ALS enzyme (also known asacetohydroxyacid synthase, AHAS) are known to confer tolerance todifferent herbicides and groups of herbicides, as described for examplein Tranel and Wright, Weed Science (2002), 50, 700-712, but also, inU.S. Pat. No. 5,605,011, U.S. Pat. No. 5,378,824, U.S. Pat. No.5,141,870, and U.S. Pat. No. 5,013,659. The production ofsulfonylurea-tolerant plants and imidazolinone-tolerant plants isdescribed in U.S. Pat. No. 5,605,011; U.S. Pat. No. 5,013,659; U.S. Pat.No. 5,141,870; U.S. Pat. No. 5,767,361; U.S. Pat. No. 5,731,180; U.S.Pat. No. 5,304,732; U.S. Pat. No. 4,761,373; U.S. Pat. No. 5,331,107;U.S. Pat. No. 5,928,937; and U.S. Pat. No. 5,378,824; and internationalpublication WO 1996/033270. Other imidazolinone-tolerant plants are alsodescribed in for example WO 2004/040012, WO 2004/106529, WO 2005/020673,WO 2005/093093, WO 2006/007373, WO 2006/015376, WO 2006/024351, and WO2006/060634. Further sulfonylurea- and imidazolinone-tolerant plants arealso described in for example WO 2007/024782.

Other plants tolerant to imidazolinone and/or sulfonylurea can beobtained by induced mutagenesis, selection in cell cultures in thepresence of the herbicide or mutation breeding as described for examplefor soybeans in U.S. Pat. No. 5,084,082, for rice in WO 1997/41218, forsugar beet in U.S. Pat. No. 5,773,702 and WO 1999/057965, for lettuce inU.S. Pat. No. 5,198,599, or for sunflower in WO 2001/065922.

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may also be treated according to theinvention are insect-resistant transgenic plants, i.e. plants maderesistant to attack by certain target insects. Such plants can beobtained by genetic transformation, or by selection of plants containinga mutation imparting such insect resistance.

An “insect-resistant transgenic plant”, as used herein, includes anyplant containing at least one transgene comprising a coding sequenceencoding:

-   -   1) an insecticidal crystal protein from Bacillus thuringiensis        or an insecticidal portion thereof, such as the insecticidal        crystal proteins listed by Crickmore et al., Microbiology and        Molecular Biology Reviews (1998), 62, 807-813, updated by        Crickmore et al. (2005) at the Bacillus thuringiensis toxin        nomenclature, online at:        http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/), or        insecticidal portions thereof, e.g., proteins of the Cry protein        classes Cry1Ab, Cry1Ac, Cry1F, Cry2Ab, Cry3Aa, or Cry3Bb or        insecticidal portions thereof; or    -   2) a crystal protein from Bacillus thuringiensis or a portion        thereof which is insecticidal in the presence of a second other        crystal protein from Bacillus thuringiensis or a portion        thereof, such as the binary toxin made up of the Cry34 and Cry35        crystal proteins (Moellenbeck et al., Nat. Biotechnol. (2001),        19, 668-72; Schnepf et al., Applied Environm. Microbiol. (2006),        71, 1765-1774); or    -   3) a hybrid insecticidal protein comprising parts of different        insecticidal crystal proteins from Bacillus thuringiensis, such        as a hybrid of the proteins of 1) above or a hybrid of the        proteins of 2) above, e.g., the Cry1A.105 protein produced by        corn event MON98034 (WO 2007/027777); or    -   4) a protein of any one of 1) to 3) above wherein some,        particularly 1 to 10, amino acids have been replaced by another        amino acid to obtain a higher insecticidal activity to a target        insect species, and/or to expand the range of target insect        species affected, and/or because of changes introduced into the        encoding DNA during cloning or transformation, such as the        Cry3Bb1 protein in corn events MON863 or MON88017, or the Cry3A        protein in corn event MIR604;    -   5) an insecticidal secreted protein from Bacillus thuringiensis        or Bacillus cereus, or an insecticidal portion thereof, such as        the vegetative insecticidal (VIP) proteins listed at:        http://www.lifesci.sussex.ac.uk/home/Neil_Crickmore/Bt/vip.html,        e.g., proteins from the VIP3Aa protein class; or    -   6) a secreted protein from Bacillus thuringiensis or Bacillus        cereus which is insecticidal in the presence of a second        secreted protein from Bacillus thuringiensis or B. cereus, such        as the binary toxin made up of the VIP1A and VIP2A proteins (WO        1994/21795); or    -   7) a hybrid insecticidal protein comprising parts from different        secreted proteins from Bacillus thuringiensis or Bacillus        cereus, such as a hybrid of the proteins in 1) above or a hybrid        of the proteins in 2) above; or    -   8) a protein of any one of 1) to 3) above wherein some,        particularly 1 to 10, amino acids have been replaced by another        amino acid to obtain a higher insecticidal activity to a target        insect species, and/or to expand the range of target insect        species affected, and/or because of changes introduced into the        encoding DNA during cloning or transformation (while still        encoding an insecticidal protein), such as the VIP3Aa protein in        cotton event COT102.

Of course, an insect-resistant transgenic plant, as used herein, alsoincludes any plant comprising a combination of genes encoding theproteins of any one of the above classes 1 to 8. In one embodiment, aninsect-resistant plant contains more than one transgene encoding aprotein of any one of the above classes 1 to 8, to expand the range oftarget insect species affected when using different proteins directed atdifferent target insect species, or to delay insect resistancedevelopment to the plants by using different proteins insecticidal tothe same target insect species but having a different mode of action,such as binding to different receptor binding sites in the insect.

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may also be treated according to theinvention are tolerant to abiotic stresses. Such plants can be obtainedby genetic transformation, or by selection of plants containing amutation imparting such stress resistance. Particularly useful stresstolerance plants include:

-   -   a. plants which contain a transgene capable of reducing the        expression and/or the activity of poly(ADP-ribose)polymerase        (PARP) gene in the plant cells or plants as described in WO        2000/004173 or WO2006/045633 or PCT/EP07/004,142.    -   b. plants which contain a stress tolerance enhancing transgene        capable of reducing the expression and/or the activity of the        PARG encoding genes of the plants or plants cells, as described        e.g. in WO 2004/090140.    -   c. plants which contain a stress tolerance enhancing transgene        coding for a plant-functional enzyme of the nicotinamide adenine        dinucleotide salvage synthesis pathway including nicotinamidase,        nicotinate phosphoribosyltransferase, nicotinic acid        mononucleotide adenyl transferase, nicotinamide adenine        dinucleotide synthetase or nicotine amide        phosphoribosyltransferase as described e.g. in WO2006/032469 or        WO 2006/133827 or PCT/EP07/002,433.

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may also be treated according to theinvention show altered quantity, quality and/or storage-stability of theharvested product and/or altered properties of specific ingredients ofthe harvested product such as:

-   -   1) transgenic plants which synthesize a modified starch, which        in its physical-chemical characteristics, in particular the        amylose content or the amylose/amylopectin ratio, the degree of        branching, the average chain length, the side chain        distribution, the viscosity behaviour, the gelling strength, the        starch grain size and/or the starch grain morphology, is changed        in comparison with the synthesised starch in wild type plant        cells or plants, so that this is better suited for special        applications. Said transgenic plants synthesizing a modified        starch are disclosed, for example, in EP 0571427, WO        1995/004826, EP 0719338, WO 1996/15248, WO 1996/19581, WO        1996/27674, WO 1997/11188, WO 1997/26362, WO 1997/32985, WO        1997/42328, WO 1997/44472, WO 1997/45545, WO 1998/27212, WO        1998/40503, WO99/58688, WO 1999/58690, WO 1999/58654, WO        2000/008184, WO 2000/008185, WO 2000/008175, WO 2000/28052, WO        2000/77229, WO 2001/12782, WO 2001/12826, WO 2002/101059, WO        2003/071860, WO 2004/056999, WO 2005/030942, WO 2005/030941, WO        2005/095632, WO 2005/095617, WO 2005/095619, WO 2005/095618, WO        2005/123927, WO 2006/018319, WO 2006/103107, WO 2006/108702, WO        2007/009823, WO 2000/22140, WO 2006/063862, WO 2006/072603, WO        2002/034923, EP 06090134.5, EP 06090228.5, EP 06090227.7, EP        07090007.1, EP 07090009.7, WO 2001/14569, WO 2002/79410, WO        2003/33540, WO 2004/078983, WO 2001/19975, WO 1995/26407, WO        1996/34968, WO 1998/20145, WO 1999/12950, WO 1999/66050, WO        1999/53072, U.S. Pat. No. 6,734,341, WO 2000/11192, WO        1998/22604, WO 1998/32326, WO 2001/98509, WO 2001/98509, WO        2005/002359, U.S. Pat. No. 5,824,790, U.S. Pat. No. 6,013,861,        WO 1994/004693, WO 1994/009144, WO 1994/11520, WO 1995/35026, WO        1997/20936.    -   2) transgenic plants which synthesize non starch carbohydrate        polymers or which synthesize non starch carbohydrate polymers        with altered properties in comparison to wild type plants        without genetic modification. Examples are plants producing        polyfructose, especially of the inulin and levan-type, as        disclosed in EP 0663956, WO 1996/001904, WO 1996/021023, WO        1998/039460, and WO 1999/024593, plants producing alpha 1,4        glucans as disclosed in WO 1995/031553, US 2002/031826, U.S.        Pat. No. 6,284,479, U.S. Pat. No. 5,712,107, WO 1997/047806, WO        1997/047807, WO 1997/047808 and WO 2000/014249, plants producing        alpha-1,6 branched alpha-1,4-glucans, as disclosed in WO        2000/73422, plants producing alternan, as disclosed in WO        2000/047727, EP 06077301.7, U.S. Pat. No. 5,908,975 and EP        0728213,    -   3) transgenic plants which produce hyaluronan, as for example        disclosed in WO 2006/032538, WO 2007/039314, WO 2007/039315, WO        2007/039316, JP 2006/304779, and WO 2005/012529.

Plants or plant cultivars (that can be obtained by plant biotechnologymethods such as genetic engineering) which may also be treated accordingto the invention are plants, such as cotton plants, with altered fibercharacteristics. Such plants can be obtained by genetic transformation,or by selection of plants contain a mutation imparting such alteredfiber characteristics and include:

-   -   a) Plants, such as cotton plants, containing an altered form of        cellulose synthase genes as described in WO 1998/000549    -   b) Plants, such as cotton plants, containing an altered form of        rsw2 or rsw3 homologous nucleic acids as described in        WO2004/053219    -   c) Plants, such as cotton plants, with increased expression of        sucrose phosphate synthase as described in WO 2001/017333    -   d) Plants, such as cotton plants, with increased expression of        sucrose synthase as described in WO02/45485    -   e) Plants, such as cotton plants, wherein the timing of the        plasmodesmatal gating at the basis of the fiber cell is altered,        e.g. through downregulation of fiberselective β 1,3-glucanase as        described in WO2005/017157    -   f) Plants, such as cotton plants, having fibers with altered        reactivity, e.g. through the expression of        N-acteylglucosaminetransferase gene including nodC and        chitinsynthase genes as described in WO2006/136351

Plants or plant cultivars (that can be obtained by plant biotechnologymethods such as genetic engineering) which may also be treated accordingto the invention are plants, such as oilseed rape or related Brassicaplants, with altered oil profile characteristics. Such plants can beobtained by genetic transformation or by selection of plants contain amutation imparting such altered oil characteristics and include:

-   -   a) Plants, such as oilseed rape plants, producing oil having a        high oleic acid content as described e.g. in U.S. Pat. No.        5,969,169, U.S. Pat. No. 5,840,946 or U.S. Pat. No. 6,323,392 or        U.S. Pat. No. 6,063,947    -   b) Plants such as oilseed rape plants, producing oil having a        low linolenic acid content as described in U.S. Pat. No.        6,270,828, U.S. Pat. No. 6,169,190 or U.S. Pat. No. 5,965,755    -   c) Plant such as oilseed rape plants, producing oil having a low        level of saturated fatty acids as described e.g. in U.S. Pat.        No. 5,434,283

Particularly useful transgenic plants which may be treated according tothe invention are plants which comprise one or more genes which encodeone or more toxins, such as the following which are sold under the tradenames YIELD GARD® (for example maize, cotton, soya beans), KnockOut®(for example maize), BiteGard® (for example maize), Bt-Xtra® (forexample maize), StarLink® (for example maize), Bollgard® (cotton),Nucotn® (cotton), Nucotn 33B® (cotton), NatureGard® (for example maize),Protecta® and NewLeaf® (potato). Examples of herbicide-tolerant plantswhich may be mentioned are maize varieties, cotton varieties and soyabean varieties which are sold under the trade names Roundup Ready®(tolerance to glyphosate, for example maize, cotton, soya bean), LibertyLink® (tolerance to phosphinotricin, for example oilseed rape), IMI®(tolerance to imidazolinones) and STS® (tolerance to sulphonylureas, forexample maize). Herbicide-resistant plants (plants bred in aconventional manner for herbicide tolerance) which may be mentionedinclude the varieties sold under the name Clearfield® (for examplemaize).

Particularly useful transgenic plants which may be treated according tothe invention are plants containing transformation events, orcombination of transformation events, that are listed for example in thedatabases from various national or regional regulatory agencies (see forexample http://gmoinfo.jrc.it/gmp_browse.aspx andhttp://www.agbios.com/dbase.php).

Among the diseases of plants or crops that can be controlled by themethod according to the present invention, mention may be made of:

Powdery mildew diseases such as:Blumeria diseases, caused for example by Blumeria gram inis;Leveillula diseases, caused for example by Leveillula tauricaPodosphaera diseases, caused for example by Podosphaera leucotricha;Sphaerotheca diseases, caused for example by Sphaerotheca fuliginea orSphaerotheca pannosa;Uncinula diseases, caused for example by Uncinula necator;Rust diseases such asGymnosporangium diseases, caused for example by Gymnosporangium sabinae;Hemileia diseases, caused for example by Hemileia vastatrix;Phakopsora diseases, caused for example by Phakopsora pachyrhizi orPhakopsora meibomiae;Puccinia diseases, caused for example by Puccinia recondita;Uromyces diseases, caused for example by Uromyces appendiculatus;Oomycete diseases such as:Bremia diseases, caused for example by Bremia lactucae;Peronospora diseases, caused for example by Peronospora pisi or P.brassicae;Phytophthora diseases, caused for example by Phytophthora infestans;Plasmopara diseases, caused for example by Plasmopara viticola;Pseudoperonospora diseases, caused for example by Pseudoperonosporahumuli orPseudoperonospora cubensis;Pythium diseases, caused for example by Pythium ultimum;Leafspot, leaf blotch and leaf blight diseases such asAlternaria diseases, caused for example by Alternaria solani;Cercospora diseases, caused for example by Cercospora beticola;Cladiosporum diseases, caused for example by Cladiosporum cucumerinum;Cochliobolus diseases, caused for example by Cochliobolus sativus;Colletotrichum diseases, caused for example by Colletotrichumlindemuthanium;Cycloconium diseases, caused for example by Cycloconium oleaginum;Diaporthe diseases, caused for example by Diaporthe citri;Diplocarpon diseases, caused for example by Diplocarpon rosaeElsinoe diseases, caused for example by Elsinoe fawcettii;Gloeosporium diseases, caused for example by Gloeosporium laeticolor;Glomerella diseases, caused for example by Glomerella cingulata;Guignardia diseases, caused for example by Guignardia bidwelli;Leptosphaeria diseases, caused for example by Leptosphaeria maculans;Leptosphaeria nodorum;Magnaporthe diseases, caused for example by Magnaporthe grisea;Mycosphaerella diseases, caused for example by Mycosphaerellagraminicola; Mycosphaerella arachidicola; Mycosphaerella fijiensis;Phaeosphaeria diseases, caused for example by Phaeosphaeria nodorum;Pyrenophora diseases, caused for example by Pyrenophora teres;Ramularia diseases, caused for example by Ramularia collo-cygni;Rhynchosporium diseases, caused for example by Rhynchosporium secalis;Septoria diseases, caused for example by Septoria apii or Septorialycopercisi;Typhula diseases, caused for example by Typhula incarnata;Venturia diseases, caused for example by Venturia inaequalis;

Root and stem diseases such as:

Corticium diseases, caused for example by Corticium graminearum;Fusarium diseases, caused for example by Fusarium oxysporum;Gaeumannomyces diseases, caused for example by Gaeumannomyces graminis;Rhizoctonia diseases, caused for example by Rhizoctonia solani;Tapesia diseases, caused for example by Tapesia acuformis;Thielaviopsis diseases, caused for example by Thielaviopsis basicola;Ear and panicle diseases such as:Alternaria diseases, caused for example by Alternaria spp.;Aspergillus diseases, caused for example by Aspergillus flavus;Cladosporium diseases, caused for example by Cladosporium spp.;Claviceps diseases, caused for example by Claviceps purpurea;Fusarium diseases, caused for example by Fusarium culmorum;Gibberella diseases, caused for example by Gibberella zeae;Monographella diseases, caused for example by Monographella nivalis;Smut and bunt diseases such as:Sphacelotheca diseases, caused for example by Sphacelotheca reiliana;Tilletia diseases, caused for example by Tilletia caries;Urocystis diseases, caused for example by Urocystis occulta;Ustilago diseases, caused for example by Ustilago nuda;Fruit rot and mould diseases such as:Aspergillus diseases, caused for example by Aspergillus flavus;Botrytis diseases, caused for example by Botrytis cinerea;Penicillium diseases, caused for example by Penicillium expansum;Sclerotinia diseases, caused for example by Sclerotinia sclerotiorum;Verticilium diseases, caused for example by Verticilium alboatrum;Seed and soilborne decay, mould, wilt, rot and damping-off diseases:Fusarium diseases, caused for example by Fusarium culmorum;Phytophthora diseases, caused for example by Phytophthora cactorum;Pythium diseases, caused for example by Pythium ultimum;Rhizoctonia diseases, caused for example by Rhizoctonia solani;Sclerotium diseases, caused for example by Sclerotium rolfsii;Microdochium diseases, caused for example by Microdochium nivale;Canker, broom and dieback diseases such as:Nectria diseases, caused for example by Nectria galligena;Blight diseases such asMonilinia diseases, caused for example by Monilinia laxa;Leaf blister or leaf curl diseases such as:Taphrina diseases, caused for example by Taphrina deformans;Decline diseases of wooden plants such as:Esca diseases, caused for example by Phaemoniella clamydospora;Diseases of flowers and Seeds such as:Botrytis diseases, caused for example by Botrytis cinerea;Diseases of tubers such as:Rhizoctonia diseases, caused for example by Rhizoctonia solani;Helminthosporium diseases, caused for example by Helminthosporiumsolani.

Furthermore the treatments according to the invention can be able toreduce the contents of mycotoxins in the harvested crops and thereforein foods and animal feed stuff made therefrom.

Especially but not exclusively the following mycotoxins can bespecified:

Deoxynivalenole (DON), Nivalenole, 15-Ac-DON, 3-Ac-DON, T2-undHT2-Toxins, Fumonisines, Zearalenone Moniliformine, Fusarine,Diaceotoxyscirpenole (DAS), Beauvericine, Enniatine, Fusaroproliferine,Fusarenole, Ochratoxines, Patuline, Ergotalcaloides und Aflatoxines,which are caused for example by the following fungal diseases: Fusariumspec., like Fusarium acuminatum, F. avenaceum, F. crookwellense, F.culmorum, F. graminearum (Gibberella zeae), F. equiseti, F. fujikoroi,F. musarum, F. oxysporum, F. proliferatum, F. poae, F.pseudograminearum, F. sambucinum, F. scirpi, F. semitectum, F. solani,F. sporotrichoides, F. langsethiae, F. subglutinans, F. tricinctum, F.verticillioides and others but also by Aspergillus spec., Penicilliumspec., Claviceps purpurea, Stachybotrys spec. and others.

The composition according to the present invention is well tolerated byplants, have favourable homeotherm toxicity and are environmentallyfriendly; it is suitable for protecting plants and plant organs, forincreasing harvest yields, for improving the quality of the harvestedmaterial and for controlling animal pests, in particular insects,arachnids and nematodes encountered in agriculture, in forests, ingardens and leisure facilities, in the protection of stored products andmaterials and in the hygiene sector. It is preferably used as cropprotection agents. It is active against normally sensitive and resistantspecies and against all or some stages of development. Among the animalpests that can also be controlled by the method according to the presentinvention, mention may be made of:

Pest from the order of the Isopoda, for example Oniscus asellus,Armadillidium vulgare and Porcellio scaber;Pest from the order of the Diplopoda, for example Blaniulus guttulatus;Pest from the order of the Chilopoda, for example Geophilus carpophagusand Scutigera spp.;Pest from the order of the Symphyla, for example Scutigerellaimmaculate;Pest from the order of the Thysanura, for example Lepisma saccharina;Pest from the order of the Collembola, for example Onychiurus armatus;Pest from the order of the Orthoptera, for example Acheta domesticus,Gryllotalpa spp., Locusta migratoria migratorioides, Melanoplus spp. andSchistocerca gregaria;Pest from the order of the Blattaria, for example Blatta orientalis,Periplaneta americana, Leucophaea maderae and Blattella germanica;Pest from the order of the Dermaptera, for example Forficulaauricularia;Pest from the order of the Isoptera, for example Reticulitermes spp.;Pest from the order of the Phthiraptera, for example Pediculus humanuscorporis, Haematopinus spp., Linognathus spp., Trichodectes spp.,Damalinia spp.;Pest from the order of the Thysanoptera, for example Hercinothripsfemoralis, Thrips tabaci, Thrips palmi, Frankliniella accidentalis;Pest from the order of the Heteroptera, for example Eurygaster spp.,Dysdercus intermedius, Piesma quadrata, Cimex lectularius,Rhodniusprolixus and Triatoma spp.;Pest from the order of the Homoptera, for example Aleurodes brassicae,Bemisia tabaci, Trialeurodes vaporariorum, Aphis gossypii, Brevicorynebrassicae, Cryptomyzus ribis, Aphis fabae, Aphis pomi, Eriosomalanigerum, Hyalopterus arundinis, Phylloxera vastatrix, Pemphigus spp.,Macrosiphum avenae, Myzus spp., Phorodon humuli, Rhopalosiphum padi,Empoasca spp., Euscelis bilobatus, Nephotettix cincticeps, Lecaniumcorni, Saissetia oleae, Laodelphax striatellus, Nilaparvata lugens,Aonidiella aurantii, Aspidiotus hederae, Pseudococcus spp. and Psyllaspp.;Pest from the order of the Lepidoptera, for example Pectinophoragossypiella, Bupalus piniarius, Chematobia brumata, Lithocolletisblancardella, Hyponomeuta padella, Plutella xylostella, Malacosomaneustria, Euproctis chrysorrhoea, Lymantria spp., Bucculatrixthurberiella, Phyllocnistis citrella, Agrotis spp., Euxoa spp., Feltiaspp., Earias insulana, Heliothis spp., Mamestra brassicae, Panolisflammea, Spodoptera spp., Trichoplusia ni, Carpocapsa pomonella, Pierisspp., Chilo spp., Pyrausta nubilalis, Ephestia kuehniella, Galleriamellonella, Tineola bisselliella, Tinea pellionella, Hofinannophilapseudospretella, Cacoecia podana, Capua reticulana, Choristoneurafumiferana, Clysia ambiguella, Homona magnanima, Tortrix viridana,Cnaphalocerus spp. and Oulema oryzae;Pest from the order of the Coleoptera, for example Anobium punctatum,Rhizopertha dominica, Bruchidius obtectus, Acanthoscelides obtectus,Hylotrupes bajulus, Agelastica alni, Leptinotarsa decemlineata, Phaedoncochleariae, Diabrotica spp., Psylliodes chrysocephala, Epilachnavarivestis, Atomaria spp., Oryzaephilus surinamensis, Anthonomus spp.,Sitophilus spp., Otiorrhynchus sulcatus, Cosmopolites sordidus,Ceuthorrhynchus assimilis, Hypera postica, Dermestes spp., Trogodermaspp., Anthrenus spp., Attagenus spp., Lyctus spp., Meligethes aeneus,Ptinus spp., Niptus hololeucus, Gibbium psylloides, Tribolium spp.,Tenebrio molitor, Agriotes spp., Conoderus spp., Melolontha melolontha,Amphimallon solstitialis, Costelytra zealandica and Lissorhoptrusoryzophilus;Pest from the order of the Hymenoptera, for example Diprion spp.,Hoplocampa spp., Lasius spp., Monomorium pharaonis and Vespa spp.;Pest from the order of the Diptera, for example Aedes spp., Anophelesspp., Culex spp., Drosophila melanogaster, Musca spp., Fannia spp.,Calliphora erythrocephala, Lucilia spp., Chrysomyia spp., Cuterebraspp., Gastrophilus spp., Hyppobosca spp., Stomoxys spp., Oestrus spp.,Hypoderma spp., Tabanus spp., Tannia spp., Bibio hortulanus, Oscinellafrit, Phorbia spp., Pegomyia hyoscyami, Ceratitis capitata, Dacus oleae,Tipula paludosa, Hylemyia spp. and Liriomyza spp.;Pest from the order of the Siphonaptera, for example Xenopsylla cheopisand Ceratophyllus spp.;Pest from the class of the Arachnida, for example Scorpio maurus,Latrodectus mactans, Acarus siro, Argas spp., Ornithodoros spp.,Dermanyssus gallinae, Eriophyes ribis, Phyllocoptruta oleivora,Boophilus spp., Rhipicephalus spp., Amblyomma spp., Hyalomma spp.,Ixodes spp., Psoroptes spp., Chorioptes spp., Sarcoptes spp., Tarsonemusspp., Bryobia praetiosa, Panonychus spp., Tetranychus spp.,Hemitarsonemus spp. and Brevipalpus spp.;The plant-parasitic nematodes such as Pratylenchus spp., Radopholussimilis, Ditylenchus dipsaci, Tylenchulus semipenetrans, Heteroderaspp., Globodera spp., Meloidogyne spp., Aphelenchoides spp., Longidorusspp., Xiphinema spp., Trichodorus spp. and Bursaphelenchus spp.

The composition according to the present invention may also be usedagainst pests and diseases liable to grow on or inside timber. The term“timber” means all types of species of wood, and all types of working ofthis wood intended for construction, for example solid wood,high-density wood, laminated wood, and plywood. The method for treatingtimber according to the invention mainly consists in contacting one ormore compounds of the present invention, or a composition according tothe invention; this includes for example direct application, spraying,dipping, injection or any other suitable means.

The dose of active material usually applied in the treatment accordingto the present invention is generally and advantageously between 10 and800 g/ha, preferably between 50 and 300 g/ha for applications in foliartreatment. If a drench/drip application is possible, the dose can belower, especially in artificial substrates like rockwool or perlite. Thedose of active substance applied is generally and advantageously between2 and 200 g per 100 kg of seed, preferably between 3 and 150 g per 100kg of seed in the case of seed treatment. It is clearly understood thatthe doses indicated above are given as illustrative examples of theinvention. A person skilled in the art will know how to adapt theapplication doses according to the nature of the crop to be treated.

The composition according to the present invention may also be used inthe treatment of genetically modified organisms with the compoundsaccording to the invention or the agrochemical compositions according tothe invention. Genetically modified plants are plants into whose genomea heterologous gene encoding a protein of interest has been stablyintegrated. The expression “heterologous gene encoding a protein ofinterest” essentially means genes which give the transformed plant newagronomic properties, or genes for improving the agronomic quality ofthe transformed plant.

BIOLOGICAL EXAMPLES Formula for the Efficacy of the Combination of TwoCompounds

The expected efficacy of a given combination of two compounds iscalculated as follows (see Colby, S. R., “Calculating Synergistic andantagonistic Responses of Herbicide Combinations”, Weeds 15, pp. 20-22,1967):

If

X is the efficacy expressed in % mortality of the untreated control fortest compound A at a concentration of m ppm respectively m g/ha,Y is the efficacy expressed in % mortality of the untreated control fortest compound B at a concentration of n ppm respectively n g/ha,E is the efficacy expressed in % mortality of the untreated controlusing the mixture of A and B at m and n ppm respectively m and n g/ha,

$E = {X + Y - \frac{X \times Y}{100}}$

If the observed insecticidal efficacy of the combination is higher thanthe one calculated as “E”, then the combination of the two compounds ismore than additive, i.e., there is a synergistic effect.

Example A Plutella xylostella—Test

Solvent: 7 parts by weight of dimethylformamide Emulsifier: 2 parts byweight of alkylaryl polyglycolether

To produce a suitable preparation of active compound, 1 part by weightof active compound is mixed with the stated amount of solvent andemulsifier, and the concentrate is diluted with emulsifier-containingwater to the desired concentration.

Cabbage leaves (Brassica oleracea) are treated by being dipped into thepreparation of the active compound of the desired concentration and areinfested with larvae of the diamond back moth (Plutella xylostella) aslong as the leaves are still moist.

After the specified period of time, the mortality in % is determined.100% means that all the caterpillars have been killed; 0% means thatnone of the caterpillars have been killed.

According to the present application in this test e.g. the followingcombinations of Table A show a synergistic effect in comparison to thesingle compounds:

TABLE A plant damaging insects Plutella xylostella - test ConcentrationEfficacy Active Ingredient in ppm in % after 4^(d) Fenamidone 500 75 20035 Imidacloprid 20 5 Thiamethoxam 4 0 obs.* cal.** Fenamidone +Imidacloprid  500 + 20 100 76.25 (25:1) according to the invention obs.*cal.** Fenamidone + Thiamethoxam 200 + 4 100 35 (50:1) according to theinvention Fenamidone 200 65 Clothianidin 4 0 obs.* cal.** Fenamidone +Clothianidin 200 + 4 100 65 (50:1) according to the invention *obs. =observed insecticidal efficacy **cal. = efficacy calculated withColby-formula

Example B Spodoptera exigua—Test

Solvent: 7 parts by weight of dimethylformamide Emulsifier: 2 parts byweight of alkylaryl polyglycolether

To produce a suitable preparation of active compound, 1 part by weightof active compound is mixed with the stated amount of solvent andemulsifier, and the concentrate is diluted with emulsifier-containingwater to the desired concentration.

Cabbage leaves (Brassica oleracea) are treated by being dipped into thepreparation of the active compound of the desired concentration and areinfested with larvae of the beet army worm (Spodoptera exigua) as longas the leaves are still moist.

After the specified period of time, the mortality in % is determined.100% means that all the caterpillars have been killed; 0% means thatnone of the caterpillars have been killed.

According to the present application in this test e.g. the followingcombinations of table B show a synergistic effect in comparison to thesingle compounds:

TABLE B plant damaging insects Spodoptera exigua - test ConcentrationEfficacy Active Ingredient in ppm in % after 3^(d) Fenamidone 100 0Thiacloprid 100 10 obs.* cal.** Fenamidone + Thiacloprid 100 + 100 35 10(1:1) erfindungsgemä

Fenamidone 200 0 Imidacloprid 20 0 obs.* cal.** Fenamidone +Imidacloprid 200 + 20  20 0 (10:1) according to the invention *obs. =observed insecticidal efficacy **cal. = efficacy calculated withColby-formula

Example C Spodoptera frugiperda—Test

Solvent: 7 parts by weight of dimethylformamide Emulsifier: 2 parts byweight of alkylaryl polyglycolether

To produce a suitable preparation of active compound, 1 part by weightof active compound is mixed with the stated amount of solvent andemulsifier, and the concentrate is diluted with emulsifier-containingwater to the desired concentration.

Cabbage leaves (Brassica oleracea) are treated by being dipped into thepreparation of the active compound of the desired concentration and areinfested with larvae of the fall army worm (Spodoptera frugiperda) aslong as the leaves are still moist.

After the specified period of time, the mortality in % is determined.100% means that all the caterpillars have been killed; 0% means thatnone of the caterpillars have been killed.

According to the present application in this test e.g. the followingcombinations of Table C show a synergistic effect in comparison to thesingle compounds:

TABLE C plant damaging insects Spodoptera frugiperda - testConcentration Efficacy Active Ingredient in ppm in % after 4^(d)Fenamidone 200 0 Clothianidin 4 0 obs.* cal.** Fenamidone + Clothianidin200 + 4 75 0 (50:1) according to the invention *obs. = observedinsecticidal efficacy **cal. = efficacy calculated with Colby-form

1. A composition comprising a) fenamidone; and b) an insecticide compound; in a (a)/(b) weight ratio of from 1/1000 to 1000/1; with the proviso that said insecticide compound is different from compounds of general formula (I)

in which Hal represents a chlorine atom, a bromine atom or a iodine atom, * represents a carbon atom in R- or S-configuration.
 2. A composition according to claim 1, wherein said insecticide compound (b) is selected from the group consisting of abamectin, acephate, acetamiprid, acrinathrin, aldicarb, alpha-cypermethrin, beta-cyfluthrin, bifenthrin, carbaryl, carbofuran, chlorfenapyr, chlorfluazuron, chlorpyrifos-E, clothianidin, cyfluthrin, cypermethrin, cyromazine, deltamethrin, diflubenzuron, diflubenzuron, dinotefuran, emamectin benzoate, ethiprole, fenpyroximate, fipronil, flonicamid, flubendiamide, flufenoxuron, gamma-cyhalothrin, hexaflumuron, imidacloprid, indoxacarb, L-cyhalothrin, lepimectin, lufenuron, methamidophos, methiocarb, methomyl, methoxyfenozide, milbemycin, nitenpyram, novaluron, profenofos, pymetrozine, rynaxapyr, spinosad, spirodiclofen, spiromesifen, spirotetramate, tebufenozide, tebufenozide, tebufenpyrad, tebufenpyrad, tebupirimphos, teflubenzuron, tefluthrin, thiacloprid, thiamethoxam, thiodicarb, triazophos and triflumuron.
 3. A composition according to claim 1 further comprising a fungicide compound (c).
 4. A composition according to claim 3, wherein compounds (a), (b) and (c) are present in an amount of (a):(b):(c) weight ratio of from 1:0.001:0.001 to 1:1000:1000.
 5. A composition according to claim 3, wherein the fungicide compound (c) is selected from the group consisting of 5-fluoro-1,3-dimethyl-N-[2-(1,3-dimethyl)-but-2-ol-yl]-1H-pyrazole-4-carboxamide, benalaxyl, benalaxyl-M, benthiavalicarb, carboxin, chlorothalonil, cyazofamid, cymoxanil, dimetomorph, fluazinam, fludioxonil, fluquinconazole, fluoxastrobin, flutriafol, fosetyl-aluminium, hexaconazole, hymexazole, ipconazole, mancozeb, mandipropamid, maneb, mefenoxam, metiram, metalaxyl, metalaxyl-M, peconazole, penthiopyrad, phosphorous acid, propamocarb.HCl, propineb, prothioconazole, tebuconazole, thiram, triadimenol, trifloxystrobin and triticonazole.
 6. A composition according to claim 1 further comprising an agriculturally acceptable support, carrier, filler and/or surfactant.
 7. A method for preventively and/or curatively controlling phytopathogenic fungi of crops but also to curatively and/or preventively controlling insects comprising applying an effective and non-phytotoxic amount of a composition according to claim 1 via seed treatment, foliar application, stem application and/or drench/drip application (chemigation) to seed, a plant and/or to fruit of a plant and/or to soil and/or to inert substrate, Pumice, a Pyroclastic material/stuff, a synthetic organic substrate, an organic substrate and/or to a liquid substrate in which a plant is growing and/or in which a plant is desired to grow.
 8. A composition according to claim 5, further Comprising an agriculturally acceptable support, carrier, filler and/or surfactant.
 9. A method for preventively or curatively controlling phytopathogenic fungi of crops but also to curatively or preventively control insects comprising applying an effective and non-phytotoxic amount of a composition according to claim 1 via seed treatment, foliar application, stem application and/or drench/drip application (chemigation) to a seed, a plant and/or to a fruit of a plant and/or to soil and/or to inert substrate, Pumice, a Pyroclastic material/stuff, a synthetic organic substrate, an organic substrate and/or to a liquid substrate in which a plant is growing or in which a plant is desired to grow.
 10. A composition according to claim 2 further comprising an agriculturally acceptable Support, carrier, filler and/or surfactant.
 11. A composition according to claim 3 further comprising an agriculturally acceptable support, carrier, filler and/or surfactant.
 12. A composition according to claim 4 further comprising an agriculturally acceptable support, carrier, filler and/or surfactant.
 13. A composition according to claim 4, wherein the fungicide compound (c) is selected from the group consisting of 5-fluoro-1,3-dimethyl-N-[2-(1,3-dimethyl)-but-2-ol-yl]-1H-pyrazole-4-carboxamide, benalaxyl, benalaxyl-M, benthiavalicarb, carboxin, chlorothalonil, cyazofamid, cymoxanil, dimetomorph, fluazinam, fludioxonil, fluquinconazole, fluoxastrobin, flutriafol, fosetyl-aluminium, hexaconazole, hymexazole, ipconazole, mancozeb, mandipropamid, maneb, mefenoxam, metiram, metalaxyl, metalaxyl-M, peconazole, penthiopyrad, phosphorous acid, propamocarb.HCl, propineb, prothioconazole, tebuconazole, thiram, triadimenol, trifloxystrobin and triticonazole.
 14. A composition according to claim 2, further comprising a fungicide compound (c). 